CURE Quote
N-of-1 RCTs are most useful when conditions are chronic and maintenance therapy is likely to be prolonged…. Similarly, treatments that have the potential to cure the underlying condition—or to lead to a permanent change in the treatment target—are not suitable for n-of-1 RCTs (Randomized Control Trials).
— Gordon Guyatt & Drummond Rennie & Maureen O. Meade & Deborah J. Cook, JAMAevidence Users’ Guides to the Medical Literature: A Manual for Evidence-Based Clinical Practice, Second Edition, 2008Archives
Monthly Archives: February 2018
Incentives to (not) Cure
There’s a lot of talk, and lots of nonsense about the high costs of medical care (often called ‘health care’). There is a fundamentally simple problem: our current medical systems have many incentives to not cure. If we want to … Continue reading
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How Many Mass Murderers Does it Take to Change a Lightbulb?
Maybe you’ve heard a few lightbulb jokes. Maybe you’ve even told a few as well. Maybe you’ve even made up a lightbulb joke? Most lightbulb jokes are fun, with little use beyond humour. Sometimes, a lightbulb joke illustrates an obvious … Continue reading
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How to Cure Bipolar Disorder
The DSM/5, the Diagnostic and Statistical Manual of Mental Disorders, is the official medical manual of mental disorders, including bipolar disorder. The headings for Bipolar Disorders include: Diagnosis | Epidemiology and Clinical Presentation | Neuroimaging | Differential Diagnosis | Treatment | … Continue reading
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The Three Mystery Causes of Illness
What causes illness? What are the basic causes of illness? If you read modern medical texts you might believe that illnesses can have thousands of causes, and then writings by alternative medical authors, perhaps every illness is caused by a … Continue reading
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